Assign MMR status by 2 IHC markers — assign

Assign MMR status by 2 IHC markers, MSH6 and PMS2.

assign_mmr2(msh6, pms2)

Arguments

msh6: MSH6 marker
pms2: PMS2 marker

Value

MMR status, either "intact" or "deficient"

Details

MMR status, intact or deficient, is determined by IHC markers MSH6 and PMS2 consolidated from TMA scoring. If both markers are intact, then MMR status is intact. Otherwise, MMR status is deficient (including subclonal and unknown markers).

Author

Samuel Leung, Derek Chiu

Examples

mmr_ihc_2 <- with(emdb, assign_mmr2(msh6, pms2))
table(mmr_ihc_2)
#> mmr_ihc_2
#> deficient    intact 
#>       164       503