Normalizes the gene expression of NanoString nCounter data to housekeeping genes. This is done by subtracting the average log housekeeping gene expression from the expression level of every gene in each sample.
Arguments
- raw
data frame of raw counts obtained from nCounter (rows represent genes, columns represent samples). The first three columns must be labeled:
c("Code.Class", "Name", "Accession")and contain that information.- is.logged
logical; If
TRUE, normalization has already been done on log base 2 scale, no need log the data- corr
small correction to avoid error
Examples
HKnorm(ovd.r)
#> Code.Class Name Accession CS1_1 CS1_2 CS1_3
#> Gene1 Endogenous Gene 1 Accession 1 -2.97732856 -3.2798380 -2.8489541
#> Gene2 Endogenous Gene 2 Accession 2 -2.64740788 -3.4318410 -3.2285975
#> Gene4 Endogenous Gene 3 Accession 3 -0.95249747 -0.5676099 -1.1958495
#> Gene5 Endogenous Gene 4 Accession 4 -3.51789649 -5.2992004 -6.7558368
#> Gene6 Endogenous Gene 5 Accession 5 -0.96734523 -3.8648000 -2.5395269
#> Gene7 Endogenous Gene 6 Accession 6 -4.68781967 -6.1163334 -7.1428573
#> Gene8 Endogenous Gene 7 Accession 7 -6.68780983 -7.9236711 -7.8432901
#> Gene9 Endogenous Gene 8 Accession 8 -1.69192693 -0.1325322 -0.7961841
#> Gene10 Endogenous Gene 9 Accession 9 -4.39236439 -7.5086396 -3.5304243
#> Gene11 Endogenous Gene 10 Accession 10 -1.64342843 -7.3387167 -4.5765197
#> Gene12 Endogenous Gene 11 Accession 11 -1.60035972 -1.3589103 -0.9853270
#> Gene13 Endogenous Gene 12 Accession 12 -4.36589223 -3.8082166 -4.7989118
#> Gene14 Endogenous Gene 13 Accession 13 -6.33988934 -7.3387167 -6.7558368
#> Gene15 Endogenous Gene 14 Accession 14 -4.82532286 -5.3387287 -5.9853221
#> Gene16 Endogenous Gene 15 Accession 15 -2.04396623 -1.7077575 -1.5372462
#> Gene17 Endogenous Gene 16 Accession 16 -6.56228004 -6.1163334 -7.2583336
#> Gene18 Endogenous Gene 17 Accession 17 0.59589691 1.7425289 -0.7705054
#> Gene19 Endogenous Gene 18 Accession 18 -5.82531926 -3.7944108 -5.6338509
#> Gene20 Endogenous Gene 19 Accession 19 -5.97732155 -0.8976327 -7.2583336
#> Gene21 Endogenous Gene 20 Accession 20 -1.26461121 -1.3337317 -2.2066831
#> Gene22 Endogenous Gene 21 Accession 21 -5.10285607 -6.3387247 -5.7558410
#> Gene23 Endogenous Gene 22 Accession 22 1.11601469 -0.8976327 0.9228067
#> Gene24 Endogenous Gene 23 Accession 23 0.56269090 -0.5544612 0.5387755
#> Gene25 Endogenous Gene 24 Accession 24 -2.95742902 -4.0168030 -4.6144875
#> Gene26 Endogenous Gene 25 Accession 25 -1.27073731 -1.1035160 -0.5776930
#> Gene27 Endogenous Gene 26 Accession 26 -2.04922196 -5.5544567 -1.8376833
#> Gene28 Endogenous Gene 27 Accession 27 -5.39236172 -2.8793003 -5.3197430
#> Gene29 Endogenous Gene 28 Accession 28 -0.47306212 -2.6444709 -5.8433036
#> Gene30 Endogenous Gene 29 Accession 29 -5.39236172 -4.5086554 -6.8432991
#> Gene31 Endogenous Gene 30 Accession 30 -7.33987903 -7.5086396 -8.0359326
#> Gene32 Endogenous Gene 31 Accession 31 -4.89932326 -2.5371136 -2.0167593
#> Gene33 Endogenous Gene 32 Accession 32 -4.24036157 -5.0823896 -5.8891072
#> Gene34 Endogenous Gene 33 Accession 33 -4.97732556 -2.0008626 -1.3941593
#> Gene35 Endogenous Gene 34 Accession 34 -1.96734498 -5.2992004 -5.7558410
#> Gene36 Endogenous Gene 35 Accession 35 -5.62368634 -3.8362309 -3.5213791
#> Gene37 Endogenous Gene 36 Accession 36 -2.48904237 -5.3793705 -6.2583396
#> Gene38 Endogenous Gene 37 Accession 37 -1.92808556 -1.7013024 -3.2359771
#> Gene39 Endogenous Gene 38 Accession 38 -4.62368947 -5.5086532 -4.3197446
#> Gene40 Endogenous Gene 39 Accession 39 -5.01796743 -6.8082069 -8.5213512
#> Gene41 Endogenous Gene 40 Accession 40 -4.03872802 -0.2232553 -1.3217075
#> Gene42 Endogenous Gene 41 Accession 41 -1.63155433 -1.2117412 -1.9606648
#> Gene43 Endogenous Gene 42 Accession 42 -4.68781967 -4.7807345 -5.4509873
#> Gene44 Endogenous Gene 43 Accession 43 -0.42274054 -1.6352133 -1.4212431
#> Gene45 Endogenous Gene 44 Accession 44 -2.73786278 -2.1292789 -2.7826116
#> Gene46 Endogenous Gene 45 Accession 45 -4.82532286 -4.7807345 -6.0884153
#> Gene47 Endogenous Gene 46 Accession 46 -4.93779730 -6.0492195 -4.8209381
#> Gene48 Endogenous Gene 47 Accession 47 -3.63945834 -2.3287481 -4.5034563
#> Gene49 Endogenous Gene 48 Accession 48 -5.05978748 -7.1867152 -5.1994490
#> Gene50 Endogenous Gene 49 Accession 49 -0.93050847 -6.5086487 -6.7558368
#> Gene51 Endogenous Gene 50 Accession 50 -1.75493671 1.1677402 -1.2415371
#> Gene52 Endogenous Gene 51 Accession 51 -5.33989449 -1.4918491 -1.7012008
#> Gene53 Endogenous Gene 52 Accession 52 -6.68780983 -5.8647957 -2.5168782
#> Gene54 Endogenous Gene 53 Accession 53 -5.19305360 -5.3387287 -7.3838634
#> Gene55 Endogenous Gene 54 Accession 54 -5.01796743 -6.4211864 -6.3197399
#> Gene56 Endogenous Gene 55 Accession 55 -2.75493628 -4.7537675 -4.4170417
#> Gene57 Endogenous Gene 56 Accession 56 -5.50339261 -3.9850942 -6.7558368
#> Gene58 Endogenous Gene 57 Accession 57 -3.26461029 -7.3387167 -6.8432991
#> Gene59 Endogenous Gene 58 Accession 58 -4.97732556 -2.9694981 -6.0359480
#> Gene60 Endogenous Gene 59 Accession 59 -3.82532467 -5.2607264 -2.6633985
#> Gene61 Endogenous Gene 60 Accession 60 -3.67151951 -5.2992004 -7.3838634
#> Gene62 Endogenous Gene 61 Accession 61 -5.44680930 -3.6017659 -3.1290619
#> Gene63 Endogenous Gene 62 Accession 62 -1.35283837 0.7610535 0.7246480
#> Gene64 Endogenous Gene 63 Accession 63 -5.56228605 -6.9236832 -7.3838634
#> Gene65 Endogenous Gene 64 Accession 64 -6.97731353 -6.4211864 -7.0359429
#> Gene66 Endogenous Gene 65 Accession 65 -4.68781967 -4.7807345 -6.8432991
#> Gene67 Endogenous Gene 66 Accession 66 -6.14724555 -0.9293416 -2.7934590
#> Gene68 Endogenous Gene 67 Accession 67 -1.86648333 -5.5086532 -1.9822209
#> Gene69 Endogenous Gene 68 Accession 68 -3.04922143 -2.6821086 -0.9637247
#> Gene70 Endogenous Gene 69 Accession 69 -4.59266264 -3.7404720 -3.4857552
#> Gene71 Endogenous Gene 70 Accession 70 -3.84347199 0.9337676 0.8739399
#> Gene72 Endogenous Gene 71 Accession 71 -6.24035435 -3.2894882 -2.8098846
#> Gene73 Endogenous Gene 72 Accession 72 -4.28927108 -7.0492129 -6.8432991
#> Gene74 Endogenous Gene 73 Accession 73 -6.05978324 -3.4211938 -7.6733671
#> Gene75 Endogenous Gene 74 Accession 74 -6.33988934 -5.9236892 -6.0884153
#> Gene76 Endogenous Gene 75 Accession 75 -5.97732155 -5.9236892 -7.5213656
#> Gene85 Endogenous Gene 76 Accession 76 -2.60809498 -4.8362295 -3.9364163
#> Gene86 Endogenous Gene 77 Accession 77 -1.74637470 -5.0823896 -4.9606626
#> Gene87 Endogenous Gene 78 Accession 78 -4.93779730 -6.0492195 -6.0359480
#> Gene88 Endogenous Gene 79 Accession 79 -2.10285990 -2.9617625 -1.4923687
#> Gene89 Endogenous Gene 80 Accession 80 -0.04134593 -5.0492228 -3.1994512
#> Gene90 Endogenous Gene 81 Accession 81 -3.21651605 -5.1867260 -6.2583396
#> Gene91 Endogenous Gene 82 Accession 82 -5.62368634 -2.8221565 -2.4128551
#> Gene93 Endogenous Gene 83 Accession 83 -3.89932515 -5.7537648 -4.6338528
#> Gene101 Endogenous Gene 84 Accession 84 -5.89931946 -5.0823896 -6.1428629
#> Gene102 Endogenous Gene 85 Accession 85 -5.24035916 -5.2992004 -2.2030628
#> Gene103 Endogenous Gene 86 Accession 86 -4.97732556 -1.3975218 -4.5213782
#> Gene106 Endogenous Gene 87 Accession 87 -4.03872802 -0.6336762 -1.7452758
#> Gene107 Endogenous Gene 88 Accession 88 -4.53254178 -5.0168014 -5.0359506
#> Gene108 Endogenous Gene 89 Accession 89 -3.24036277 -2.3897161 -1.8746410
#> Gene109 Endogenous Gene 90 Accession 90 -1.59266533 -4.8362295 -4.6534816
#> Gene110 Endogenous Gene 91 Accession 91 -3.72098813 -2.9161999 -4.8660259
#> Gene111 Endogenous Gene 92 Accession 92 -4.56228906 -7.0492129 -7.1428573
#> Gene112 Endogenous Gene 93 Accession 93 -5.50339261 -3.7272967 -1.0751236
#> Gene113 Endogenous Gene 94 Accession 94 -2.28306780 -3.4533742 -1.3696022
#> Gene114 Endogenous Gene 95 Accession 95 -0.08926271 -1.0574464 -1.1868831
#> Gene115 Endogenous Gene 96 Accession 96 -5.10285607 -3.7404720 -2.6683819
#> Gene116 Endogenous Gene 97 Accession 97 -1.77656672 -2.2140365 -1.4296800
#> Gene117 Endogenous Gene 98 Accession 98 -2.90884887 -0.9598356 -2.3474527
#> Gene118 Endogenous Gene 99 Accession 99 -2.41254427 -4.8939449 -5.3838732
#> Gene119 Endogenous Gene 100 Accession 100 -7.33987903 -7.3387167 -7.6733671
#> Gene120 Endogenous Gene 101 Accession 101 -5.97732155 -7.9236711 -7.0359429
#> Gene121 Endogenous Gene 102 Accession 102 -3.88046615 -5.6506717 -5.5213764
#> Gene122 Endogenous Gene 103 Accession 103 -2.97732856 0.4906378 -4.7347816
#> Gene123 Endogenous Gene 104 Accession 104 -2.51062922 -3.9850942 -5.4170400
#> Gene124 Endogenous Gene 105 Accession 105 -4.78969904 -6.4211864 -6.2583396
#> Gene125 Endogenous Gene 106 Accession 106 -1.38238264 -2.1423350 -1.8775235
#> Gene126 Endogenous Gene 107 Accession 107 -3.89932515 -1.9464149 -3.2810649
#> Gene127 Endogenous Gene 108 Accession 108 -5.44680930 -7.9236711 -3.7243660
#> Gene128 Endogenous Gene 109 Accession 109 -0.04003736 -5.4642592 -6.3197399
#> Gene129 Endogenous Gene 110 Accession 110 -5.14725006 -5.2232518 -6.5953730
#> Gene130 Endogenous Gene 111 Accession 111 1.66130750 0.3647865 0.7782860
#> Gene131 Endogenous Gene 112 Accession 112 -3.16997350 -5.7537648 -5.9364127
#> Gene132 Endogenous Gene 113 Accession 113 -2.09740547 -6.8082069 -5.8891072
#> Gene133 Endogenous Gene 114 Accession 114 -4.56228906 -3.8648000 -4.0104168
#> CS1_4 CS1_5 CS1_6 CS1_7 CS1_8
#> Gene1 -3.7893444 -3.91492175 -3.0584915 -3.755183438 -2.97162034
#> Gene2 -3.4332007 -3.15654340 -3.3326663 -3.347840582 -0.37978278
#> Gene4 -2.1015949 -1.66486796 -0.3838926 -0.987845068 -1.05922711
#> Gene5 -7.6742026 -4.90149991 -5.5365346 -7.087370586 -7.56579073
#> Gene6 -0.8774320 -1.51428277 -1.1992362 -0.417989508 -4.06656822
#> Gene7 -5.2029023 -6.48645707 -4.4370017 -6.435297637 -5.56579906
#> Gene8 -8.2267406 -6.19695191 -6.5365294 -8.894699747 -6.94430624
#> Gene9 -1.1301228 -0.41321598 -1.5462328 -1.194295922 -0.31933520
#> Gene10 -6.0043557 -5.84903001 -4.4612492 -5.222307643 -4.98083748
#> Gene11 -4.1168320 -4.40846067 -3.8360984 -5.765448675 -6.35934614
#> Gene12 -1.6969291 -1.63958152 -1.2458623 0.182079850 -2.99011668
#> Gene13 -7.4897788 -6.40845498 -3.9515755 -5.724806805 -4.74267803
#> Gene14 -5.5042827 -5.13282499 -6.0219594 -6.987835600 -7.01830644
#> Gene15 -6.3262833 -5.33445838 -4.7291819 -6.194290546 -5.94430985
#> Gene16 -0.9524885 -2.26407223 -1.6024273 -1.796703467 -0.87822416
#> Gene17 -6.4057176 -6.84902486 -3.7439803 -4.590953239 -6.80680337
#> Gene18 1.2507383 4.38325727 3.4654716 3.260952088 1.77302026
#> Gene19 -6.3522785 -5.10179816 -5.3438902 -6.572800505 -4.51135271
#> Gene20 -7.9637078 -7.65637205 -5.5890018 -6.724802797 -3.74267881
#> Gene21 -0.8604279 -1.25551044 -2.0538754 -2.129863891 -0.39202854
#> Gene22 -2.7306286 -4.98396191 -4.0219648 -5.435300916 -5.59381338
#> Gene23 1.5676657 1.25537642 1.3395387 1.989243879 2.30716897
#> Gene24 2.2741581 0.62438074 0.5164165 1.729145699 -0.50054098
#> Gene25 -2.4790046 -3.73752566 -3.2043423 -3.637347028 -5.53831837
#> Gene26 -1.8928493 -0.65638994 -2.2146111 -0.840809796 -3.06656871
#> Gene27 -6.3787506 -1.88490029 -2.9430144 -1.663514393 -3.06656871
#> Gene28 -6.6742059 -6.56891876 -4.3215246 -4.850339508 -6.56579628
#> Gene29 -1.5915762 -1.44207072 -1.8086189 -4.519694644 -3.25501373
#> Gene30 -5.1002167 -4.21344493 -2.0355552 -4.294821484 -6.05678428
#> Gene31 -10.1336047 -7.19694535 -6.7589201 -6.250873853 -8.26622352
#> Gene32 -6.3007483 -6.13282186 -4.5890045 -4.402881114 -5.24387152
#> Gene33 -3.9587146 -2.01614479 -3.4735287 -6.309767301 -5.71164963
#> Gene34 -5.3007495 -5.79840412 -2.8926827 -1.515357230 -5.48487921
#> Gene35 -4.8482377 -5.19695519 -3.7291833 -6.572800505 -3.81502961
#> Gene36 -6.6100757 -6.33445478 -5.1344374 -4.590953239 -3.31787373
#> Gene37 -6.3007483 -5.61199159 -4.7000356 -5.987840409 3.52109990
#> Gene38 -3.3522808 -3.46656454 -2.4984040 -3.468470220 -2.19477892
#> Gene39 -7.5486723 -6.84902486 -4.2353681 -4.807270851 -3.79863518
#> Gene40 -6.7073727 -6.07142157 -23.6316070 -9.309725224 -7.45887632
#> Gene41 -3.9940889 -3.88820444 -3.8844614 -3.180489609 -3.51804803
#> Gene42 -2.4647556 -2.47648050 -2.9515764 -1.377066228 -2.12158305
#> Gene43 -6.0251142 -6.56891876 -4.8844598 -6.309767301 -5.98083563
#> Gene44 -1.7860193 -2.21344617 -1.8480392 -2.791447480 -2.16295348
#> Gene45 -1.4358044 -2.09796899 -0.8400687 -1.427130060 -3.89120125
#> Gene46 -6.6100757 -6.74948987 -4.1941455 -6.572800505 -4.71165116
#> Gene47 -5.9637138 -8.07140354 -5.4859087 -5.685278549 -3.64418900
#> Gene48 -3.0172966 -1.18065645 0.5187428 -1.546007438 -4.92638977
#> Gene49 -7.8117055 -6.95593927 -5.2564276 -6.646800707 -3.68881197
#> Gene50 -2.1678564 -3.44693574 -3.1247252 -7.894717780 -3.32960302
#> Gene51 -1.6680743 -2.74350015 -1.1320061 -1.750077316 -0.39510629
#> Gene52 -5.9637138 -6.84902486 -5.3438902 -2.750077061 -4.26624042
#> Gene53 -9.5486543 -7.65637205 -6.4369945 -1.018218713 -8.94428460
#> Gene54 -5.4471389 -7.48644905 -2.2831982 0.693041750 -7.45887632
#> Gene55 -7.0461737 -6.56891876 -4.7000356 -0.001434207 -6.87391726
#> Gene56 -4.1057342 -4.67910787 -1.1941473 0.289519744 -3.92639066
#> Gene57 -5.9048202 -6.56891876 -5.4369993 -4.451790659 -7.26623253
#> Gene58 -4.4125409 -5.95594482 -3.8203311 -6.435297637 -7.94429903
#> Gene59 -4.9438152 -2.02339452 -1.4551511 -2.100319622 -5.11649240
#> Gene60 -5.1112719 -5.19695519 -1.9387528 -5.222307643 -4.74267803
#> Gene61 -3.9144718 -2.32996015 -2.1890760 -5.572804112 -6.94430624
#> Gene62 -1.4700826 -3.72565157 -2.6434543 -6.987835600 0.67480609
#> Gene63 -1.0974671 0.09766237 -1.4612513 1.782543400 0.04664146
#> Gene64 -5.8298582 -7.19694535 -5.2994962 -8.087360282 -7.35934134
#> Gene65 -7.4331955 -8.33443314 -6.0219594 -7.572793292 -4.26624042
#> Gene66 -4.9838927 -7.84901455 -4.2146096 -7.572793292 -4.94431165
#> Gene67 -4.5790512 -5.61199159 -6.2564233 -2.675566809 -6.87391726
#> Gene68 0.2905255 -3.49651774 -2.9688544 -1.009039288 -3.30623904
#> Gene69 -3.4683045 -3.40846162 -3.2353692 -2.661115657 -2.19477892
#> Gene70 -4.0408831 -4.40846067 -3.0401130 -3.229399186 -2.98083887
#> Gene71 -3.6298147 -5.26406923 -3.5494775 -1.584122805 -3.25501373
#> Gene72 -5.7242482 -6.74948987 -5.5890018 -3.928950375 -3.76639487
#> Gene73 -6.0251142 -5.90149724 -4.1941455 -6.987835600 -3.94431255
#> Gene74 -5.4612140 -7.65637205 -6.2564233 -7.724794782 -8.94428460
#> Gene75 -7.3787480 -6.84902486 -5.6434494 -6.646800707 -4.10636920
#> Gene76 -7.4897788 -5.84903001 -4.2778033 -4.807270851 -0.81709280
#> Gene85 -4.1336402 -4.35260751 -4.3438924 -5.036752331 -0.76440427
#> Gene86 -2.0134028 -7.07141556 -6.1739616 -5.646804503 -2.27471942
#> Gene87 -5.0892456 -5.01253101 -4.4859112 -6.894726797 -5.22184524
#> Gene88 -2.3086819 -3.78602413 -2.8926827 -2.861312261 -1.43969290
#> Gene89 -1.4168212 -1.41321586 -2.3896978 -3.572806817 -0.79659963
#> Gene90 -1.0251163 -5.70218912 -3.2353692 -5.987840409 -6.51134870
#> Gene91 -4.4541600 -4.26407094 -2.9430144 -3.493855523 -3.00885324
#> Gene93 -5.4754279 -4.65638783 -3.4612504 -5.222307643 -0.74072064
#> Gene101 -4.5411830 -6.13282186 -5.7000327 -7.435291079 -7.80679682
#> Gene102 -6.3522785 -6.19695191 -4.5110021 -3.646807351 -2.18675650
#> Gene103 -2.9662224 -1.04721116 -0.7778404 -2.180489952 -3.22732201
#> Gene106 -6.7760853 -5.04167730 -4.3666125 -3.765451766 -6.13695441
#> Gene107 -4.9737684 -5.65638558 -4.4131550 -6.036749844 -4.69638442
#> Gene108 -2.2388229 -3.91492175 -2.3495407 -1.934733592 -1.72902295
#> Gene109 -6.2756573 -6.56891876 -2.4797079 -3.215255010 -4.35934975
#> Gene110 -1.0205497 -2.38026521 -2.0219661 -4.435302555 -5.40825807
#> Gene111 -1.3190582 -7.65637205 -5.3896937 -7.724794782 -7.26623253
#> Gene112 -7.3262807 -6.74948987 -4.8844598 -4.355575451 -4.48488052
#> Gene113 -2.9487652 -2.92846895 -2.8047351 -2.714826226 -3.56580114
#> Gene114 -1.8321445 -1.94903061 -2.8360992 -3.024370477 -0.38819056
#> Gene115 -7.5486723 -6.95593927 -4.9176266 -3.572806817 -4.08633146
#> Gene116 -2.1750879 -2.04905940 -1.8762887 -1.692611745 -0.55285495
#> Gene117 -4.5713976 -3.23853673 -3.1150750 -2.423060193 -5.87392069
#> Gene118 -4.7499356 -5.79840412 -4.2353681 -5.340143892 -6.01831024
#> Gene119 -8.8116983 -8.07140354 -7.5365191 -7.309761290 -3.92639066
#> Gene120 -8.1336318 -7.33444756 -6.0219594 -7.087370586 0.52451424
#> Gene121 -1.4297371 -4.16453539 -3.0677693 -2.100319622 -4.69638442
#> Gene122 1.7701469 -4.13282656 -2.4984040 -3.139847643 -5.11649240
#> Gene123 -3.4506459 -5.33445838 -4.8844598 -6.036749844 -7.09630853
#> Gene124 -6.7760853 -6.65638107 -5.7589262 -7.309761290 -6.87391726
#> Gene125 -4.2088277 -3.51683771 -3.3552088 -2.204737493 -1.61339640
#> Gene126 -4.6990117 -3.81089878 -2.8203319 -4.309771810 -3.57974032
#> Gene127 -8.0461695 -5.07142458 -4.3215246 -4.153267479 -0.49475200
#> Gene128 -6.2756573 -5.56892300 -4.6714665 -7.087370586 -6.94430624
#> Gene129 -7.1794398 -6.19695191 -4.8520384 -6.572800505 -5.48487921
#> Gene130 0.4449678 0.77249352 0.9859017 1.881491596 2.58384760
#> Gene131 -3.4193949 -2.61747055 -3.1054890 -4.685280498 -6.56579628
#> Gene132 -2.1071172 -1.54004586 -2.0631234 -4.724808808 -5.45888405
#> Gene133 -4.8207569 -4.56892512 -4.1344393 -4.180488922 -3.38972399
#> CS1_9 CS1_10 CS1_11 CS1_12 CS1_13
#> Gene1 -3.25590605 -3.89050459 -3.69558489 -3.453619531 -3.64736620
#> Gene2 -3.86224147 -3.32707551 -2.83221985 -3.386982362 -2.64094015
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#> CS2_15 CS2_16 CS2_17 CS2_18 CS2_19
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#> CS2_20 CS2_21 CS2_22 CS2_23 CS2_24
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#> Gene52 -7.27793965 -7.930945e+00 -7.95038603 -1.37910996 -2.1406271
#> Gene53 -8.27792161 -9.930923e+00 -9.21340360 -3.17107254 -1.0319983
#> Gene54 -0.99718668 -8.004945e+00 -7.14303626 -8.03730954 -5.4770294
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#> Gene59 -2.44506703 -6.144354e+00 -3.35545096 -4.72746509 -4.4176515
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#> Gene62 -3.37106588 -6.793445e+00 -2.37045337 -2.52952666 -1.8019927
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#> Gene64 -6.37105747 -7.165413e+00 -5.55807834 -7.92183325 -5.8172580
#> Gene65 -7.95600073 -9.445505e+00 -9.95034996 -7.71538385 -8.2019153
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#> Gene69 -4.37106468 -3.103133e+00 -2.39325324 -2.24507332 -1.5162011
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#> Gene88 -1.67062700 -1.599139e+00 -3.08827691 -2.02237104 -0.8331744
#> Gene89 0.47023525 1.851319e-01 -0.46456867 -3.13043057 -2.4337389
#> Gene90 -4.92040216 -1.542935e+00 -0.51091336 -6.33687815 -6.4411087
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#> Gene129 -6.95601516 -8.252871e+00 -8.53534252 -8.16283933 -7.9124102
#> Gene130 2.04114993 -7.483781e-02 -1.72157920 2.07923901 1.6048053
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#> Gene133 -4.69299217 -4.587544e+00 -4.74094338 -3.41771243 -4.7065117
#> CS2_25 CS2_26 CS2_27 CS2_28 CS2_29
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#> Gene5 -6.6732495 -3.829951463 -7.07780628 -7.73264090 -1.51732390
#> Gene6 0.1781485 -1.698422515 0.04457842 -0.16089124 1.02983554
#> Gene7 -5.5952491 -6.495829285 -5.75588539 -5.95128331 -4.91586140
#> Gene8 -10.2581680 -8.874317603 -23.95049318 -6.82575170 -6.79029554
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#> Gene13 -5.3837453 -4.986819237 -4.90789063 -6.11793308 -5.56793060
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#> Gene17 -6.4856230 -7.736829818 -7.34083828 -7.45962292 -7.37523400
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#> Gene19 -4.8097544 -3.838721668 -4.90789063 -6.14768040 -5.05336361
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#> Gene23 1.3613926 2.408162861 1.60459116 2.36659431 4.03408483
#> Gene24 1.9572159 1.531858570 2.06365028 3.47800208 3.72798171
#> Gene25 -2.7770891 -3.910871408 -3.23651521 -1.13397099 -0.82071651
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#> Gene130 1.7694596 1.254163506 2.36339681 2.10472122 2.82068123
#> Gene131 -5.5763901 -7.388909325 -6.34084549 -4.77457420 -21.66301851
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#> Gene133 -5.1849656 -4.538061641 -5.04806801 -4.88297776 -3.98298184
#> CS2_30 CS2_31 CS2_32 CS2_33 CS2_34
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#> Gene18 3.9297126 0.553346871 4.04225565 2.0274555 4.2128174
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#> Gene28 -5.2925132 -4.025345047 -5.88710213 -4.5708359 -6.5766391
#> Gene29 -0.8944151 -7.062526261 -0.63657849 0.8108991 2.7217659
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#> Gene75 -7.56796151 -2.44058712 -6.94782630 -5.73738145 -7.45221078
#> Gene76 0.57720163 -9.04047141 -1.17116334 -4.10802788 -1.97829526
#> Gene85 -4.49757642 -7.04049305 -3.43777331 -5.12267317 -2.92171140
#> Gene86 -10.15289997 -8.36241032 -7.94782115 -8.15239941 -6.30021650
#> Gene87 -6.66749942 -7.36241934 -5.75518412 -7.56744493 -0.65636738
#> Gene88 -1.23168288 -3.85463292 -8.43324385 -6.73737694 -2.05609739
#> Gene89 -1.16879517 -0.58188851 -1.18818091 -2.36669811 -0.06852242
#> Gene90 -9.66748139 -6.55506828 -8.75516834 -9.15237537 -3.88068348
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#> Gene109 -4.18483761 -5.36242610 -3.10413432 -3.42450209 -4.49286674
#> Gene110 -2.30368000 0.48932072 -0.65781254 1.10771204 -1.78610114
#> Gene111 -3.83823194 -6.07702244 -8.29574164 0.18296697 2.26982172
#> Gene112 -9.47483889 -4.67592643 -1.87254317 -4.52793064 -9.62207968
#> Gene113 -3.07825192 -2.78878079 -1.51320310 -2.13005527 -2.34138058
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#> Gene116 -2.26906355 -1.09915904 -0.92863781 -1.20990875 -1.44473203
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#> Gene127 -6.47485466 -5.04049846 2.41747553 -0.90766306 -5.62214730
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#> CS2_128 CS2_129
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#> Gene2 -1.07108290 0.74795179
#> Gene4 -0.45097451 -0.21325669
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#> Gene9 -0.59866319 -0.77723923
#> Gene10 -5.52102131 -6.15436017
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#> Gene12 -2.91940817 -1.31944952
#> Gene13 -4.88667104 -5.71075428
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#> Gene15 -2.03764734 -7.55028413
#> Gene16 0.04042268 0.51806232
#> Gene17 -6.28942945 -6.58876198
#> Gene18 3.86930737 0.28093220
#> Gene19 -4.83222327 -5.71075428
#> Gene20 -0.03684540 -0.44341884
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#> Gene22 -6.24133520 -5.60839271
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#> Gene25 -4.46126694 -3.70018663
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#> Gene119 -3.01094171 1.32023525
#> Gene120 3.31417996 -0.35268697
#> Gene121 -4.60221773 -1.63080097
#> Gene122 -4.28637704 -3.61830965
#> Gene123 -6.06354822 -6.37195113
#> Gene124 -9.58709920 -6.79821473
#> Gene125 -2.39153387 -3.38882788
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#> Gene127 -1.27915146 1.84642572
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#> Gene129 -5.19479322 -0.66893616
#> Gene130 1.21277748 0.59275579
#> Gene131 -6.21787625 -6.62829023
#> Gene132 -5.43736342 -6.01685690
#> Gene133 -4.57216051 -5.27465572
HKnorm(ovd.r, is.logged = TRUE)
#> Code.Class Name Accession CS1_1 CS1_2 CS1_3 CS1_4
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#> Gene2 Endogenous Gene 2 Accession 2 -3856.2 -7266.2 -6368.6 -22952.6
#> Gene4 Endogenous Gene 3 Accession 3 -3451.2 -6418.2 -5762.6 -22321.6
#> Gene5 Endogenous Gene 4 Accession 4 -3938.2 -7364.2 -6547.6 -23346.6
#> Gene6 Endogenous Gene 5 Accession 5 -3457.2 -7301.2 -6248.6 -20922.6
#> Gene7 Endogenous Gene 6 Accession 6 -3993.2 -7380.2 -6551.6 -23246.6
#> Gene8 Endogenous Gene 7 Accession 7 -4026.2 -7395.2 -6556.6 -23353.6
#> Gene9 Endogenous Gene 8 Accession 8 -3686.2 -6072.2 -5506.6 -21315.6
#> Gene10 Endogenous Gene 9 Accession 9 -3983.2 -7393.2 -6405.6 -23298.6
#> Gene11 Endogenous Gene 10 Accession 10 -3674.2 -7392.2 -6487.6 -23109.6
#> Gene12 Endogenous Gene 11 Accession 11 -3663.2 -6833.2 -5636.6 -21982.6
#> Gene13 Endogenous Gene 12 Accession 12 -3982.2 -7297.2 -6498.6 -23343.6
#> Gene14 Endogenous Gene 13 Accession 13 -4023.2 -7392.2 -6547.6 -23269.6
#> Gene15 Endogenous Gene 14 Accession 14 -3997.2 -7365.2 -6535.6 -23312.6
#> Gene16 Endogenous Gene 15 Accession 15 -3762.2 -6955.2 -5931.6 -21046.6
#> Gene17 Endogenous Gene 16 Accession 16 -4025.2 -7380.2 -6552.6 -23315.6
#> Gene18 Endogenous Gene 17 Accession 17 -2323.2 -2526.2 -5487.6 -12675.6
#> Gene19 Endogenous Gene 18 Accession 18 -4017.2 -7296.2 -6527.6 -23313.6
#> Gene20 Endogenous Gene 19 Accession 19 -4019.2 -6619.2 -6552.6 -23350.6
#> Gene21 Endogenous Gene 20 Accession 20 -3565.2 -6823.2 -6166.6 -20893.6
#> Gene22 Endogenous Gene 21 Accession 21 -4004.2 -7383.2 -6530.6 -22691.6
#> Gene23 Endogenous Gene 22 Accession 22 -1579.2 -6619.2 -3081.6 -10048.6
#> Gene24 Endogenous Gene 23 Accession 23 -2362.2 -6409.2 -3895.6 -1632.6
#> Gene25 Endogenous Gene 24 Accession 24 -3891.2 -7311.2 -6489.6 -22562.6
#> Gene26 Endogenous Gene 25 Accession 25 -3567.2 -6723.2 -5333.6 -22158.6
#> Gene27 Endogenous Gene 26 Accession 26 -3763.2 -7370.2 -6050.6 -23314.6
#> Gene28 Endogenous Gene 27 Accession 27 -4010.2 -7203.2 -6518.6 -23324.6
#> Gene29 Endogenous Gene 28 Accession 28 -3220.2 -7168.2 -6532.6 -21877.6
#> Gene30 Endogenous Gene 29 Accession 29 -4010.2 -7337.2 -6548.6 -23237.6
#> Gene31 Endogenous Gene 30 Accession 30 -4030.2 -7393.2 -6557.6 -23364.6
#> Gene32 Endogenous Gene 31 Accession 31 -3999.2 -7150.2 -6110.6 -23311.6
#> Gene33 Endogenous Gene 32 Accession 32 -3977.2 -7358.2 -6533.6 -23079.6
#> Gene34 Endogenous Gene 33 Accession 33 -4001.2 -7037.2 -5865.6 -23254.6
#> Gene35 Endogenous Gene 34 Accession 34 -3747.2 -7364.2 -6530.6 -23212.6
#> Gene36 Endogenous Gene 35 Accession 35 -4014.2 -7299.2 -6404.6 -23322.6
#> Gene37 Endogenous Gene 36 Accession 36 -3835.2 -7366.2 -6540.6 -23311.6
#> Gene38 Endogenous Gene 37 Accession 37 -3739.2 -6953.2 -6369.6 -22928.6
#> Gene39 Endogenous Gene 38 Accession 38 -3991.2 -7369.2 -6472.6 -23344.6
#> Gene40 Endogenous Gene 39 Accession 39 -4002.2 -7388.2 -6559.6 -23325.6
#> Gene41 Endogenous Gene 40 Accession 40 -3968.2 -6153.2 -5829.6 -23086.6
#> Gene42 Endogenous Gene 41 Accession 41 -3671.2 -6772.2 -6092.6 -22554.6
#> Gene43 Endogenous Gene 42 Accession 42 -3993.2 -7348.2 -6522.6 -23299.6
#> Gene44 Endogenous Gene 43 Accession 43 -3191.2 -6932.2 -5878.6 -22065.6
#> Gene45 Endogenous Gene 44 Accession 44 -3867.2 -7068.2 -6297.6 -21707.6
#> Gene46 Endogenous Gene 45 Accession 45 -3997.2 -7348.2 -6537.6 -23322.6
#> Gene47 Endogenous Gene 46 Accession 46 -4000.2 -7379.2 -6499.6 -23296.6
#> Gene48 Endogenous Gene 47 Accession 47 -3946.2 -7111.2 -6483.6 -22813.6
#> Gene49 Endogenous Gene 48 Accession 48 -4003.2 -7391.2 -6514.6 -23348.6
#> Gene50 Endogenous Gene 49 Accession 49 -3442.2 -7385.2 -6547.6 -22368.6
#> Gene51 Endogenous Gene 50 Accession 50 -3701.2 -4128.2 -5787.6 -21954.6
#> Gene52 Endogenous Gene 51 Accession 51 -4009.2 -6883.2 -5999.6 -23296.6
#> Gene53 Endogenous Gene 52 Accession 52 -4026.2 -7376.2 -6243.6 -23362.6
#> Gene54 Endogenous Gene 53 Accession 53 -4006.2 -7365.2 -6553.6 -23265.6
#> Gene55 Endogenous Gene 54 Accession 54 -4002.2 -7384.2 -6541.6 -23334.6
#> Gene56 Endogenous Gene 55 Accession 55 -3869.2 -7347.2 -6478.6 -23107.6
#> Gene57 Endogenous Gene 56 Accession 56 -4012.2 -7309.2 -6547.6 -23293.6
#> Gene58 Endogenous Gene 57 Accession 57 -3919.2 -7392.2 -6548.6 -23157.6
#> Gene59 Endogenous Gene 58 Accession 58 -4001.2 -7215.2 -6536.6 -23222.6
#> Gene60 Endogenous Gene 59 Accession 59 -3957.2 -7363.2 -6274.6 -23238.6
#> Gene61 Endogenous Gene 60 Accession 60 -3948.2 -7364.2 -6553.6 -23070.6
#> Gene62 Endogenous Gene 61 Accession 61 -4011.2 -7281.2 -6354.6 -21746.6
#> Gene63 Endogenous Gene 62 Accession 62 -3593.2 -4932.2 -3528.6 -21268.6
#> Gene64 Endogenous Gene 63 Accession 63 -4013.2 -7389.2 -6553.6 -23289.6
#> Gene65 Endogenous Gene 64 Accession 64 -4028.2 -7384.2 -6550.6 -23342.6
#> Gene66 Endogenous Gene 65 Accession 65 -3993.2 -7348.2 -6548.6 -23226.6
#> Gene67 Endogenous Gene 66 Accession 66 -4021.2 -6636.2 -6299.6 -23180.6
#> Gene68 Endogenous Gene 67 Accession 67 -3726.2 -7369.2 -6099.6 -17872.6
#> Gene69 Endogenous Gene 68 Accession 68 -3900.2 -7174.2 -5622.6 -22962.6
#> Gene70 Endogenous Gene 69 Accession 69 -3990.2 -7292.2 -6400.6 -23095.6
#> Gene71 Endogenous Gene 70 Accession 70 -3958.2 -4618.2 -3197.6 -23005.6
#> Gene72 Endogenous Gene 71 Accession 71 -4022.2 -7252.2 -6302.6 -23283.6
#> Gene73 Endogenous Gene 72 Accession 72 -3979.2 -7390.2 -6548.6 -23299.6
#> Gene74 Endogenous Gene 73 Accession 73 -4020.2 -7265.2 -6555.6 -23266.6
#> Gene75 Endogenous Gene 74 Accession 74 -4023.2 -7377.2 -6537.6 -23341.6
#> Gene76 Endogenous Gene 75 Accession 75 -4019.2 -7377.2 -6554.6 -23343.6
#> Gene85 Endogenous Gene 76 Accession 76 -3851.2 -7350.2 -6444.6 -23112.6
#> Gene86 Endogenous Gene 77 Accession 77 -3699.2 -7358.2 -6505.6 -22255.6
#> Gene87 Endogenous Gene 78 Accession 78 -4000.2 -7379.2 -6536.6 -23236.6
#> Gene88 Endogenous Gene 79 Accession 79 -3773.2 -7214.2 -5911.6 -22461.6
#> Gene89 Endogenous Gene 80 Accession 80 -2935.2 -7357.2 -6364.6 -21685.6
#> Gene90 Endogenous Gene 81 Accession 81 -3915.2 -7361.2 -6540.6 -21160.6
#> Gene91 Endogenous Gene 82 Accession 82 -4014.2 -7195.2 -6219.6 -23163.6
#> Gene93 Endogenous Gene 83 Accession 83 -3961.2 -7374.2 -6490.6 -23267.6
#> Gene101 Endogenous Gene 84 Accession 84 -4018.2 -7358.2 -6538.6 -23175.6
#> Gene102 Endogenous Gene 85 Accession 85 -4007.2 -7364.2 -6165.6 -23313.6
#> Gene103 Endogenous Gene 86 Accession 86 -4001.2 -6848.2 -6484.6 -22793.6
#> Gene106 Endogenous Gene 87 Accession 87 -3968.2 -6462.2 -6016.6 -23327.6
#> Gene107 Endogenous Gene 88 Accession 88 -3988.2 -7356.2 -6508.6 -23225.6
#> Gene108 Endogenous Gene 89 Accession 89 -3917.2 -7123.2 -6063.6 -22416.6
#> Gene109 Endogenous Gene 90 Accession 90 -3661.2 -7350.2 -6491.6 -23310.6
#> Gene110 Endogenous Gene 91 Accession 91 -3951.2 -7208.2 -6501.6 -21153.6
#> Gene111 Endogenous Gene 92 Accession 92 -3989.2 -7390.2 -6551.6 -21567.6
#> Gene112 Endogenous Gene 93 Accession 93 -4012.2 -7291.2 -5692.6 -23340.6
#> Gene113 Endogenous Gene 94 Accession 94 -3804.2 -7268.2 -5853.6 -22786.6
#> Gene114 Endogenous Gene 95 Accession 95 -2971.2 -6701.2 -5757.6 -22106.6
#> Gene115 Endogenous Gene 96 Accession 96 -4004.2 -7292.2 -6275.6 -23344.6
#> Gene116 Endogenous Gene 97 Accession 97 -3706.2 -7087.2 -5882.6 -22373.6
#> Gene117 Endogenous Gene 98 Accession 98 -3886.2 -6652.2 -6203.6 -23179.6
#> Gene118 Endogenous Gene 99 Accession 99 -3824.2 -7352.2 -6520.6 -23201.6
#> Gene119 Endogenous Gene 100 Accession 100 -4030.2 -7392.2 -6555.6 -23358.6
#> Gene120 Endogenous Gene 101 Accession 101 -4019.2 -7395.2 -6550.6 -23352.6
#> Gene121 Endogenous Gene 102 Accession 102 -3960.2 -7372.2 -6524.6 -21700.6
#> Gene122 Endogenous Gene 103 Accession 103 -3893.2 -5354.2 -6495.6 -8041.6
#> Gene123 Endogenous Gene 104 Accession 104 -3838.2 -7309.2 -6521.6 -22957.6
#> Gene124 Endogenous Gene 105 Accession 105 -3996.2 -7384.2 -6540.6 -23327.6
#> Gene125 Endogenous Gene 106 Accession 106 -3602.2 -7071.2 -6064.6 -23125.6
#> Gene126 Endogenous Gene 107 Accession 107 -3961.2 -7023.2 -6375.6 -23195.6
#> Gene127 Endogenous Gene 108 Accession 108 -4011.2 -7395.2 -6425.6 -23351.6
#> Gene128 Endogenous Gene 109 Accession 109 -2934.2 -7368.2 -6541.6 -23310.6
#> Gene129 Endogenous Gene 110 Accession 110 -4005.2 -7362.2 -6545.6 -23337.6
#> Gene130 Endogenous Gene 111 Accession 111 -450.2 -5525.2 -3413.6 -17251.6
#> Gene131 Endogenous Gene 112 Accession 112 -3911.2 -7374.2 -6534.6 -22948.6
#> Gene132 Endogenous Gene 113 Accession 113 -3772.2 -7388.2 -6533.6 -22325.6
#> Gene133 Endogenous Gene 114 Accession 114 -3989.2 -7301.2 -6450.6 -23209.6
#> CS1_5 CS1_6 CS1_7 CS1_8 CS1_9 CS1_10 CS1_11 CS1_12
#> Gene1 -4329.8 -3516.8 -8170.2 -9008.8 -4078.2 -10731 -12517.2 -12478.6
#> Gene2 -4255.8 -3543.8 -8124.2 -7429.8 -4113.2 -10645 -12313.2 -12465.6
#> Gene4 -3927.8 -2676.8 -7351.2 -8140.8 -3791.2 -9871 -11695.2 -11229.6
#> Gene5 -4382.8 -3644.8 -8297.2 -9309.8 -4173.2 -10892 -12612.2 -12729.6
#> Gene6 -3871.8 -3106.8 -6886.2 -9175.8 -3483.2 -8391 -11197.2 -10603.6
#> Gene7 -4418.8 -3612.8 -8289.2 -9270.8 -4155.2 -10886 -12703.2 -12666.6
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